購(gòu)物車 
-
Tretoquinol
- names：
1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol
- CAS號(hào)：
30418-38-3
MDL Number： - MF(分子式)： C19H23NO MW(分子量)： 345.395
- EINECS: Reaxys Number:
- Pubchem ID: Brand:BIOFOUNT
| 貨品編碼 | 規(guī)格 | 純度 | 價(jià)格 (￥) | 現(xiàn)價(jià)(￥) | 特價(jià)(￥) | 庫(kù)存描述 | 數(shù)量 | 總計(jì) (￥) |
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| 中文別名 | 1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol |
| 英文別名 | Tretoquinol; tretoquinol hydrochloride; AQ-110; AQ110; AQ 110 |
| CAS號(hào) | 30418-38-3 |
| Inchi | InChI=1S/C19H23NO5/c1-23-17-7-11(8-18(24-2)19(17)25-3)6-14-13-10-16(22)15(21)9-12(13)4-5-20-14/h7-10,14,20-22H,4-6H2,1-3H3 |
| InchiKey | RGVPOXRFEPSFGH-UHFFFAOYSA-N |
| 分子式 Formula | C19H23NO |
| 分子量 Molecular Weight | 345.395 |
| 溶解度Solubility | |
| 性狀 | Solid powder |
| 儲(chǔ)藏條件 Storage conditions | Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years). |
| 產(chǎn)品說(shuō)明 | Tretoquinol(CAS:30418-38-3 ):僅限應(yīng)用于工業(yè)或者科學(xué)研究過(guò)程中非醫(yī)療目的，不應(yīng)用于人類或動(dòng)物的臨床診斷以及治過(guò)程療，該產(chǎn)品非藥用，非食用。 |
| Introduction | Tretoquinol, also known as AQ-110 and tretoquinol hydrochloride, is a β2-adrenergic receptor agonist used to treat asthma and chronic obstructive pulmonary disease. Although Tretoquinol possesses a catechol group, it was found not to be a substrate for catechol-O-methyl transferase and this is considered to account for its significantly prolonged action. |
| Application1 | |
| Application2 | |
| Application3 |
| [1]Contu VR, Kotake Y, Toyama T, Okuda K, Miyara M, Sakamoto S, Samizo S, Sanoh S, Kumagai Y, Ohta S. Endogenous neurotoxic dopamine derivative covalently binds to Parkinson's disease-associated ubiquitin C-terminal hydrolase L1 and alters its structure and function. J Neurochem. 2014 Sep;130(6):826-38. doi: 10.1111/jnc.12762. Epub 2014 Jun 18. PubMed PMID: 24832624. |
| [2]Whiting DM, Tomycz ND, Bailes J, de Jonge L, Lecoultre V, Wilent B, Alcindor D, Prostko ER, Cheng BC, Angle C, Cantella D, Whiting BB, Mizes JS, Finnis KW, Ravussin E, Oh MY. Lateral hypothalamic area deep brain stimulation for refractory obesity: a pilot study with preliminary data on safety, body weight, and energy metabolism. J Neurosurg. 2013 Jul;119(1):56-63. doi: 10.3171/2013.2.JNS12903. Epub 2013 Apr 5. PubMed PMID: 23560573. |
| [3] Fogelman F, Grundy HF. A comparison of the cardiovascular actions of AQ 110 with those of isoprenaline and salbutamol. Br J Pharmacol. 1970 Feb;38(2):416-32. PubMed PMID: 4392103; PubMed Central PMCID: PMC1702809. |
| [4] Kretschmer L, Pratsch AL. Leg swelling after inguinal sentinel lymph node biopsy and primary melanoma excision with a safety margin. J Dtsch Dermatol Ges. 2012 Oct;10(10):733-9. doi: 10.1111/j.1610-0387.2012.07941.x. Epub 2012 Jun 12. PubMed PMID: 22686498. |
| [5] Nelson MR, Lanza LA, Reeder CB, Scott RL, McCullough AE, Chandrasekaran K, Click RL. Histologic remission of cardiac amyloidosis: a case report. Amyloid. 2012 Jun;19(2):106-9. doi: 10.3109/13506129.2012.660892. Epub 2012 Mar 7. PubMed PMID: 22394355. |
6: Dainese L, Guarino A, Burba I, Esposito G, Pompilio G, Polvani G, Rossini A. Heart valve engineering: decellularized aortic homograft seeded with human cardiac stromal cells. J Heart Valve Dis. 2012 Jan;21(1):125-34. PubMed PMID: 22474754.7: Nakajima H, Hoshiyama M, Kiyomoto A. [Studies on tetrahydroisoquinolines. V. Actions of 1-(3, 4, 5-trimethoxybenzyl)-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline HCL (AQ-110) on the guinea-pig papillary muscle]. Nihon Yakurigaku Zasshi. 1969 Mar 20;65(2):34-9. Japanese. PubMed PMID: 5387676.8: Iwasawa Y, Kiyomoto A. [Studies on tetrahydroisoquinoline compounds. (3). Pharmacodynamics of 1-(3,4,5-trimethoxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline HC1 (AQ-110)]. Nihon Yakurigaku Zasshi. 1967 Mar 20;63(2):28-42. Japanese. PubMed PMID: 4383100.9: Comer BT, Young AB, Gal TJ. Impact of endoscopic surgical techniques on efficiency in pituitary surgery. Otolaryngol Head Neck Surg. 2011 Nov;145(5):732-6. doi: 10.1177/0194599811416753. Epub 2011 Jul 22. PubMed PMID: 21785043.10: Richards D, Davis D, Yan P, Guha S. Unusual case of small cell gastric carcinoma: case report and literature review. Dig Dis Sci. 2011 Apr;56(4):951-7. doi: 10.1007/s10620-010-1404-1. Epub 2010 Sep 18. Review. PubMed PMID: 20848201.
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