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Sarcophytol A

NMR下載 COA and HPLC MSDS下載
names：
(S,2Z,4E,8E,12E)-2-isopropyl-5,9,13-trimethylcyclotetradeca-2,4,8,12-tetraen-1-ol
CAS號：
72629-69-7
MDL Number：
MF(分子式)： C20H32O MW(分子量)： 288.47
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	(S,2Z,4E,8E,12E)-2-isopropyl-5,9,13-trimethylcyclotetradeca-2,4,8,12-tetraen-1-ol
英文別名	Sarcophytol A; Sarcophytol-A;
CAS號	72629-69-7
Inchi	InChI=1S/C20H32O/c1-15(2)19-13-12-17(4)10-6-8-16(3)9-7-11-18(5)14-20(19)21/h8,11-13,15,20-21H,6-7,9-10,14H2,1-5H3/b16-8+,17-12+,18-11+,19-13-/t20-/m0/s1
InchiKey	YADVRLOQIWILGX-MIWLTHJTSA-N
分子式 Formula	C20H32O
分子量 Molecular Weight	288.47
溶解度Solubility
性狀	Solid powder
儲藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產品說明	Sarcophytol A(CAS:72629-69-7):僅限應用于工業或者科學研究過程中非醫療目的，不應用于人類或動物的臨床診斷以及治過程療，該產品非藥用，非食用。
Introduction	Sarcophytol A is a cembrane-type diterpene isolated from the marine soft coral Sarcophyton glaucum that has anticancer effects.
Application1
Application2
Application3

警示圖
危險性	Warning
危險性警示
安全聲明
安全防護
備注

[1]Yokomatsu H, Satake K, Hiura A, Tsutsumi M, Suganuma M. Sarcophytol A: a new chemotherapeutic and chemopreventive agent for pancreatic cancer. Pancreas. 1994 Jul;9(4):526-30. PubMed PMID: 7937700.

[2]Yamauchi O, Omori M, Ninomiya M, Okuno M, Moriwaki H, Suganuma M, Fujiki H, Muto Y. Inhibitory effect of sarcophytol A on development of spontaneous hepatomas in mice. Jpn J Cancer Res. 1991 Nov;82(11):1234-8. PubMed PMID: 1684357; PubMed Central PMCID: PMC5918333.

[3] Wei H, Frenkel K. Suppression of tumor promoter-induced oxidative events and DNA damage in vivo by sarcophytol A: a possible mechanism of antipromotion. Cancer Res. 1992 Apr 15;52(8):2298-303. PubMed PMID: 1559232.

[4] Koh M, Iwanaga T, Hatanaka M, Nakano A, Morihara K, Takemura K. Distribution of sarcophytol A in soft coral of the Sarcophyton genus. Biosci Biotechnol Biochem. 2000 Apr;64(4):858-61. PubMed PMID: 10830506.

[5] Kobayashi M, Kobayashi K, Nomura M, Munakata H. Conformational study of the cembranoid sarcophytol A, a potent anti-tumor-promoter. Chem Pharm Bull (Tokyo). 1990 Mar;38(3):815-7. PubMed PMID: 2347029.

6: Kobayashi M, Kondo K, Osabe K, Mitsuhashi H. Marine terpenes and terpenoids. V. Oxidation of sarcophytol A, a potent anti-tumor-promoter from the soft coral Sarcophyton glaucum. Chem Pharm Bull (Tokyo). 1988 Jul;36(7):2331-41. PubMed PMID: 2907304.7: Yokomatsu H, Hiura A, Tsutsumi M, Satake K. Inhibitory effect of sarcophytol A on pancreatic carcinogenesis after initiation by N-nitrosobis(2-oxypropyl)amine in Syrian hamsters. Pancreas. 1996 Aug;13(2):154-9. PubMed PMID: 8829183.8: Weitberg AB, Corvese D. The effect of epigallocatechin galleate and sarcophytol A on DNA strand breakage induced by tobacco-specific nitrosamines and stimulated human phagocytes. J Exp Clin Cancer Res. 1999 Sep;18(3):433-7. PubMed PMID: 10606191.9: Narisawa T, Takahashi M, Niwa M, Fukaura Y, Fujiki H. Inhibition of methylnitrosourea-induced large bowel cancer development in rats by sarcophytol A, a product from a marine soft coral Sarcophyton glaucum. Cancer Res. 1989 Jun 15;49(12):3287-9. PubMed PMID: 2720682.10: Nakagane T, Ishitani R. Presence of specific binding sites for [3H]sarcophytol-A in cultured human skin fibroblasts. Experientia. 1990 May 15;46(5):490-2. PubMed PMID: 2347400.1

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